Human Glomerular Microvascular Endothelial Cells


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Human glomerular microvascular endothelial cells (HGMECs) cover the luminal surface of glomerular capillaries and function to regulate vasomotor tone, blood hemostasis, and filtration of leukocytes. Glomerular endothelial cells are usually flattened and have characteristic 50-100 nm fenestrae which contribute to the permeability of the glomerular filtration barrier. HGMECs express bioactive molecules to modulate local milieu and to cross-talk with other glomerular cells, including vasoactive factors, thrombotic regulators and inflammatory modulators. Due to its vital role in blood filtration, dysfunction of the HGMECs is closely associated with pre-eclampsia, thrombotic microangiopathies, diabetic nephropathy, proteinuria, and glomerulosclerosis.

Why choose Human Glomerular Microvascular Endothelial Cells from AcceGen?

HGMECs are isolated from human kidneys using AcceGen??s advanced technology. Cells at passage one are cryopreserved with each vial contains more than 5??10^5 cells in 1ml volume. HGMECs are tested for expression of endothelial specific markers vWF/Factor VIII and/or??CD31 using immunofluorescence. HGMECs are guaranteed for further expansion of 5 populations following protocols provided by AcceGen.

Weight 0.5 kg
Dimensions 10 × 2 × 2 cm

HGMECs can be potential ?research target for developing future therapeutic interventions for chronic kidney disease or restoration of filtration capability after injury.

Biosafety Level




Product Type

Renal Cells




1 vial

Shipping Info

Dry Ice


Liquid Nitrogen



Source Organ


Cell Type


Citation Guide

please cite our product as ??AcceGen Biotech Cat.# XXX-0000??. In return, we??ll give you a $100 coupon. Simply click here and submit your paper??s PubMed ID (PMID)., When you publish your research


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